| Galio | Akali, Katarina, Mage-heavy Comps | Frontline, anti-dive, and AoE crowd control. |
| Ryze | Akali, Katarina, Sylas, LeBlanc | Sustained damage, side-lane pressure, and team repositioning. |
| Viktor | Yasuo, Yone, Talon, Ryze, Azir | Sustained AoE damage and zone control. |
| Lissandra | Yasuo, Yone, Akali, LeBlanc | Anti-dive, pick potential, and AoE teamfight control. |
| Anivia | Yasuo, Yone, Sylas, Ekko, Locke | Defensive zoning, anti-dive, and objective control. |
| Azir | Ryze, Aurora, Anivia, Annie | Sustained DPS, zone control, and disengage. |
| Orianna | Galio, Cassiopeia, Ryze | AoE control, shielding, and teamfight combos. |
| Syndra | Aurora, Zoe, Veigar, LeBlanc | Burst damage and pick potential. |
| Xerath | Lux | Long-range poke and siege. |
| Hwei | Cassiopeia, Veigar, Ryze | Long-range poke, AoE damage, and zone control. |
| Cassiopeia | Diana, Locke, Vex, Yasuo | Sustained DPS, anti-dive, and close-range zone control. |
| Veigar | Ryze, Zoe, Vladimir | Burst damage and area denial. |
| Ahri | Orianna, Veigar, Immobile Mages | Picks, mobility, and follow-up engage. |
| Jayce | Vex, Ekko, Sylas, Akali | Poke, burst, and siege. |
| Yone | Veigar, Xerath, Immobile Long-range Mages | Backline dive and AoE engage. |
| Lucian | Ryze, Veigar, Short-range Mages | Early pressure and skirmishing. |
| Pantheon | Zed, Talon, Xerath, Aurelion Sol | Point-and-click lockdown and roaming. |